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Rabbit anti-Human RAP1GDS1 Polyclonal Antibody

The antibody against RAP1GDS1 was raised in rabbit using the Human RAP1GDS1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-52116A

The antibody against RAP1GDS1 was raised in rabbit using the Human RAP1GDS1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-52116A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRAP1GDS1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman RAP1GDS1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP52306
Background Information
  • Uniprot Id

    P52306

  • Target Species

    Human

  • Target Name

    RAP1GDS1

  • Target Full Name

    Rap1 GTPase-GDP dissociation stimulator 1

  • Target Function

    Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein. Able to promote the Ca(2+) release from the endoplasmic reticulum via both inositol trisphosphate (Ins3P) and ryanodine sensitive receptors leading to a enhanced mitochondrial Ca(2+) uptake.

  • Target Subcellular Location

    Cytoplasm, cytosol. Endoplasmic reticulum. Mitochondrion.

  • Target Synonyms

    Exchange factor smgGDS; GDP dissociation stimulator 1; GDS1; GDS1_HUMAN; GTP-GDP dissociation stimulator 1; GTPase-GDP dissociation stimulator; Rap1; 1; Highly similar to RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1; MGC118859; MGC118861; RAP1; Rap1 GTPase-GDP dissociation stimulator 1; RAP1GDS1; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein; SMGGDS

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