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The antibody against RARS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RARS (NP_002878.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against RARS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RARS (NP_002878.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-09509A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RARS |
| Target Synonyms | HLD9; RARS; ArgRS; DALRD1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, U-251MG | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RARS (NP_002878.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P54136 | Immunogen Sequence |
Uniprot Id
P54136
Target Species
Human
Target Name
RARS1
Target Full Name
Arginine--tRNA ligase, cytoplasmic
Target Function
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.
Target Involvement
Leukodystrophy, hypomyelinating, 9 (HLD9)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytosol.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
2610011N19Rik; 2610037E21Rik; AL033339; Arginine tRNA ligase 1, cytoplasmic; Arginine tRNA ligase; Arginine--tRNA ligase; Arginyl tRNA synthetase 1; Arginyl tRNA synthetase cytoplasmic; Arginyl tRNA synthetase, cytoplasmic; Arginyl-tRNA synthetase, cytoplasmic; ArgRS; AW985894; DALRD 1; DALRD1; EC 6.1.1.19; MGC8641; MGC86730; RARS; SYRC_HUMAN; wu:fa96g09; zgc:56050; zgc:86730
Target Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Arginyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family.
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