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The antibody against RARS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 17-340 of human RARS2 (NP_064716.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RARS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 17-340 of human RARS2 (NP_064716.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01241A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RARS2 |
| Target Synonyms | PCH6; ArgRS; RARSL; DALRD2; PRO1992; RARS2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, K-562 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 17-340 of human RARS2 (NP_064716.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5T160 | Immunogen Sequence |
Uniprot Id
Q5T160
Target Species
Human
Target Name
RARS2
Target Full Name
Probable arginine--tRNA ligase, mitochondrial
Target Involvement
Pontocerebellar hypoplasia 6 (PCH6)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
arginine tRNA ligase; arginyl tRNA synthetase 2 mitochondrial; Arginyl tRNA synthetase; Arginyl-tRNA synthetase; ArgRS; DALRD2; mitochondrial; PCH6; Probable arginine tRNA ligase; probable arginine tRNA ligase mitochondrial; Probable arginine--tRNA ligase; probable arginyl tRNA synthetase mitochondrial; RARS2; RARSL; SYRM_HUMAN
Target Background
This nuclear gene encodes a protein that localizes to the mitochondria, where it catalyzes the transfer of L-arginine to its cognate tRNA, an important step in translation of mitochondrially-encoded proteins. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6). Alternative splicing results in multiple transcript variants.
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