Rabbit anti-Human RASGRF1 Polyclonal Antibody

The antibody against RASGRF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RASGRF1 (NP_001139120.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09402A

Number

Cat.No	ADA-09402A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RASGRF1
Target Synonyms	GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1; RASGRF1	Form	Liquid
Species Reactivity	Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse brain	Application	ELISA, WB

Cat.No

ADA-09402A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RASGRF1

Target Synonyms

GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1; RASGRF1

Form

Liquid

Species Reactivity

Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse brain

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RASGRF1 (NP_001139120.1).	Target Species	Human
Immunogen Sequence	MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITSLLKDNERIQS	Uniprot ID	Q13972

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human RASGRF1 (NP_001139120.1).

Target Species

Human

Immunogen Sequence

MQKGIRLNDGHVASLGLLARKDGTRKGYLSKRSSDNTKWQTKWFALLQNLLFYFESDSSSRPSGLYLLEGCVCDRAPSPKPALSAKEPLEKQHYFTVNFSHENQKALELRTEDAKDCDEWVAAIAHASYRTLATEHEALMQKYLHLLQIVETEKTVAKQLRQQIEDGEIEIERLKAEITSLLKDNERIQS

Uniprot ID

Q13972

Background Information

Uniprot Id

Q13972
Target Species

Human
Target Name

RASGRF1
Target Full Name

Ras-specific guanine nucleotide-releasing factor 1
Target Function

Promotes the exchange of Ras-bound GDP by GTP.
Target Synonyms

CDC25 ; CDC25L; GNRP; GRF1 ; GRF55 ; Guanine nucleotide exchange factor ; Guanine nucleotide releasing factor 55 kD; Guanine nucleotide releasing protein ; guanine nucleotide-releasing factor 1; Guanine nucleotide-releasing protein; H GRF55; HGRF55; PP13187 ; Ras protein specific guanine nucleotide releasing factor 1 ; Ras specific guanine nucleotide releasing factor; Ras specific guanine nucleotide releasing factor CDC25 homolog; Ras specific nucleotide exchange factor CDC25; Ras-GRF1; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific nucleotide exchange factor CDC25; RASGRF1; RGRF1_HUMAN
Target Background

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Rabbit anti-Human RASGRF1 Polyclonal Antibody

Specifications

Immunogen Information

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