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The antibody against RBM11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human RBM11 (NP_658983.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RBM11 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human RBM11 (NP_658983.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03525A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RBM11 |
| Target Synonyms | RBM11 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, MCF7, Mouse testis, Rat testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human RBM11 (NP_658983.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P57052 | Immunogen Sequence |
Uniprot Id
P57052
Target Species
Human
Target Name
RBM11
Target Full Name
Splicing regulator RBM11
Target Function
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
Target Subcellular Location
Nucleus, nucleoplasm. Nucleus speckle. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
Target Tissue Specificity
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
Target Synonyms
RBM11; Splicing regulator RBM11; RNA-binding motif protein 11
Target Background
Enables poly(U) RNA binding activity and protein homodimerization activity. Acts upstream of or within cellular response to oxidative stress and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck.
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