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The antibody against RBM11 was raised in rabbit using the Recombinant Human Splicing regulator RBM11 protein (115-278AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RBM11 was raised in rabbit using the Recombinant Human Splicing regulator RBM11 protein (115-278AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using RBM11 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using RBM11 Antibody at dilution of 1:1002
| Cat.No | ADC-22506A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RBM11 |
| Target Synonyms | RBM11 antibody; Splicing regulator RBM11 antibody; RNA-binding motif protein 11 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Splicing regulator RBM11 protein (115-278AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P57052 |
Uniprot Id
P57052
Target Species
Human
Target Name
RBM11
Target Full Name
Splicing regulator RBM11
Target Function
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
Target Subcellular Location
Nucleus, nucleoplasm. Nucleus speckle. Note=Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
Target Tissue Specificity
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
Target Synonyms
RBM11; Splicing regulator RBM11; RNA-binding motif protein 11
Target Background
Enables poly(U) RNA binding activity and protein homodimerization activity. Acts upstream of or within cellular response to oxidative stress and regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck.
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