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The antibody against RBM38 was raised in rabbit using the Recombinant Human RNA-binding protein 38 protein (1-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against RBM38 was raised in rabbit using the Recombinant Human RNA-binding protein 38 protein (1-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human brain tissue using RBM38 Antibody at dilution of 1:100
Immunofluorescent analysis of A549 cells using RBM38 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-10066A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RBM38 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human RNA-binding protein 38 protein (1-239AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H0Z9 |
Uniprot Id
Q9H0Z9
Target Species
Human
Target Name
RBM38
Target Full Name
RNA-binding protein 38
Target Function
RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.; (Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
RBM38 family
Target Synonyms
CLL associated antigen KW 5 ; CLL-associated antigen KW-5; HSRNASEB; RBM38; RBM38_HUMAN; RNA binding motif protein 38; RNA binding protein 38 ; RNA binding region (RNP1; RRM) containing 1 ; RNA binding region containing protein 1 ; RNA-binding motif protein 38; RNA-binding protein 38; RNA-binding region-containing protein 1; RNPC1 ; SEB4; SEB4B; SEB4D; ssDNA binding protein SEB4 ; ssDNA-binding protein SEB4
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