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Rabbit anti-Human RBSN Polyclonal Antibody

The antibody against RBSN was raised in rabbit using the Recombinant Human Rabenosyn-5 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-17953A

The antibody against RBSN was raised in rabbit using the Recombinant Human Rabenosyn-5 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-17953A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRBSN
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Rabenosyn-5 protein (201-500AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9H1K0
Background Information
  • Uniprot Id

    Q9H1K0

  • Target Species

    Human

  • Target Name

    RBSN

  • Target Full Name

    Rabenosyn-5

  • Target Function

    Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3). Plays a role in the recycling of transferrin receptor to the plasma membrane.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor.

  • Target Synonyms

    110 kDa protein; FYVE finger containing Rab5 effector protein Rabenosyn 5; FYVE finger-containing Rab5 effector protein rabenosyn-5; Rabenosyn-5; RBNS5_HUMAN; Zfyve20; zinc finger FYVE domain containing 20; Zinc finger FYVE domain-containing protein 20

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