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The antibody against RCN3 was raised in rabbit using the Recombinant Human Reticulocalbin-3 protein (71-161AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against RCN3 was raised in rabbit using the Recombinant Human Reticulocalbin-3 protein (71-161AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-03865A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RCN3 |
| Target Synonyms | EF-hand calcium binding domain antibody; Reticulocalbin-3 antibody; RLP49 antibody; UNQ239/PRO272 antibody, EF-hand calcium-binding protein RLP49 antibody; RCN3 antibody; RCN3_HUMAN antibody; reticulocalbin 3 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Reticulocalbin-3 protein (71-161AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96D15 |
Uniprot Id
Q96D15
Target Species
Human
Target Name
RCN3
Target Full Name
Reticulocalbin-3
Target Function
Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens. This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion.
Target Subcellular Location
Endoplasmic reticulum lumen.
Target Protein Families
CREC family
Target Tissue Specificity
Widely expressed.
Target Synonyms
EF-hand calcium-binding protein RLP49; RCN3; RCN3_HUMAN; reticulocalbin 3, EF-hand calcium binding domain; Reticulocalbin-3; RLP49; UNQ239/PRO272
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