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Rabbit anti-Human RECQL5 Polyclonal Antibody

The antibody against RECQL5 was raised in rabbit using the Human RECQL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-52080A

The antibody against RECQL5 was raised in rabbit using the Human RECQL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-52080A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRECQL5
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman RECQL5Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO94762
Background Information
  • Uniprot Id

    O94762

  • Target Species

    Human

  • Target Name

    RECQL5

  • Target Full Name

    ATP-dependent DNA helicase Q5

  • Target Function

    Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.

  • Target Subcellular Location

    [Isoform Beta]: Nucleus, nucleoplasm.; [Isoform Alpha]: Cytoplasm.; [Isoform Gamma]: Cytoplasm.

  • Target Protein Families

    Helicase family, RecQ subfamily

  • Target Tissue Specificity

    Ubiquitous.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    ATP-dependent DNA helicase Q5; DNA helicase; DNA helicase; RecQ like type 5; DNA helicase; RECQ-like; type 5; EC 3.6.1.-; FLJ90603; RecQ helicase protein-like 5 beta ; RecQ protein-like 5; RecQ protein-like 5; isoform CRA_b; RecQ-like type 5; RecQ5; RECQ5_HUMAN; Recq5b; RECQL5; Recql5b

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