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The antibody against RECQL5 was raised in rabbit using the Human RECQL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against RECQL5 was raised in rabbit using the Human RECQL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-52080A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RECQL5 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human RECQL5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O94762 |
Uniprot Id
O94762
Target Species
Human
Target Name
RECQL5
Target Full Name
ATP-dependent DNA helicase Q5
Target Function
Isoform beta is a DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
Target Subcellular Location
[Isoform Beta]: Nucleus, nucleoplasm.; [Isoform Alpha]: Cytoplasm.; [Isoform Gamma]: Cytoplasm.
Target Protein Families
Helicase family, RecQ subfamily
Target Tissue Specificity
Ubiquitous.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
ATP-dependent DNA helicase Q5; DNA helicase; DNA helicase; RecQ like type 5; DNA helicase; RECQ-like; type 5; EC 3.6.1.-; FLJ90603; RecQ helicase protein-like 5 beta ; RecQ protein-like 5; RecQ protein-like 5; isoform CRA_b; RecQ-like type 5; RecQ5; RECQ5_HUMAN; Recq5b; RECQL5; Recql5b
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