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The antibody against RFNG was raised in rabbit using the Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase radical fringe protein (71-331AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against RFNG was raised in rabbit using the Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase radical fringe protein (71-331AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
Western Blot | Positive WB detected in: HepG2 whole cell lysate, 293 whole cell lysate, PC3 whole cell lysate, Rat brain tissue | All lanes: RFNG antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 37 kDa | Observed band size: 37 kDa
| Cat.No | ADC-01755A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RFNG |
| Target Synonyms | 3-N-acetylglucosaminyltransferase radical fringe antibody; EC 2.4.1.222 antibody; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, RFNG antibody; Beta-1 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase radical fringe protein (71-331AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y644 |
Uniprot Id
Q9Y644
Target Species
Human
Target Name
RFNG
Target Full Name
Beta-1,3-N-acetylglucosaminyltransferase radical fringe
Target Function
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in enhancement of NOTCH1 activation by DLL1 and JAG1. May be involved in limb formation and in neurogenesis.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 31 family
Target Synonyms
RFNG; Beta-1,3-N-acetylglucosaminyltransferase radical fringe; EC 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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