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The antibody against RGS7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RGS7 (NP_002915.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RGS7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RGS7 (NP_002915.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02875A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RGS7 |
| Target Synonyms | RGS7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human RGS7 (NP_002915.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P49802 | Immunogen Sequence |
Uniprot Id
P49802
Target Species
Human
Target Name
RGS7
Target Full Name
Regulator of G-protein signaling 7
Target Function
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS7/GNB5 dimer enhances GNAO1 GTPase activity. May play a role in synaptic vesicle exocytosis. Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling.
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side.
Target Research Area
Signal Transduction
Target Synonyms
RGS7; Regulator of G-protein signaling 7; RGS7
Target Background
Enables G-protein beta-subunit binding activity and GTPase activator activity. Involved in positive regulation of GTPase activity. Located in cytosol.
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