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The antibody against RHBDF2 was raised in rabbit using the Recombinant Human Inactive rhomboid protein 2 protein (1-200aa) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against RHBDF2 was raised in rabbit using the Recombinant Human Inactive rhomboid protein 2 protein (1-200aa) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-54953A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RHBDF2 |
| Target Synonyms | Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6), IRHOM2 RHBDL5 RHBDL6, RHBDF2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Inactive rhomboid protein 2 protein (1-200aa) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6PJF5 |
Uniprot Id
Q6PJF5
Target Species
Human
Target Name
RHBDF2
Target Full Name
Inactive rhomboid protein 2
Target Function
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.
Target Involvement
Tylosis with esophageal cancer (TOC)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.
Target Protein Families
Peptidase S54 family
Target Tissue Specificity
Found in the epidermis and esophageal epithelium.
Target Synonyms
RHBDF2; IRHOM2; RHBDL5; RHBDL6; Inactive rhomboid protein 2; iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6
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