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Rabbit anti-Human RHBDF2 Polyclonal Antibody, Biotin conjugated

The antibody against RHBDF2 was raised in rabbit using the Recombinant Human Inactive rhomboid protein 2 protein (1-200aa) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-54954A

The antibody against RHBDF2 was raised in rabbit using the Recombinant Human Inactive rhomboid protein 2 protein (1-200aa) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-54954A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRHBDF2
Target SynonymsInactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6), IRHOM2 RHBDL5 RHBDL6, RHBDF2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateBiotin conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Inactive rhomboid protein 2 protein (1-200aa)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6PJF5
Background Information
  • Uniprot Id

    Q6PJF5

  • Target Species

    Human

  • Target Name

    RHBDF2

  • Target Full Name

    Inactive rhomboid protein 2

  • Target Function

    Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

  • Target Involvement

    Tylosis with esophageal cancer (TOC)

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane.

  • Target Protein Families

    Peptidase S54 family

  • Target Tissue Specificity

    Found in the epidermis and esophageal epithelium.

  • Target Synonyms

    RHBDF2; IRHOM2; RHBDL5; RHBDL6; Inactive rhomboid protein 2; iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6

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