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The antibody against RHEBL1 was raised in rabbit using the Recombinant Human GTPase RhebL1 protein (1-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RHEBL1 was raised in rabbit using the Recombinant Human GTPase RhebL1 protein (1-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human ovarian cancer using RHEBL1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human appendix tissue using RHEBL1 Antibody at dilution of 1:1002
| Cat.No | ADC-23839A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RHEBL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human GTPase RhebL1 protein (1-180AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TAI7 |
Uniprot Id
Q8TAI7
Target Species
Human
Target Name
RHEBL1
Target Full Name
GTPase RhebL1
Target Function
Binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B-mediated gene transcription. Promotes signal transduction through MTOR, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Target Subcellular Location
Endomembrane system; Lipid-anchor; Cytoplasmic side. Cytoplasm.
Target Protein Families
Small GTPase superfamily, Rheb family
Target Tissue Specificity
Ubiquitously expressed. Expression increased at least 2-fold in several tumor cell lines.
Target Synonyms
RHEBL1; GTPase RhebL1; Ras homolog enriched in brain like-1 c; RhebL1c; Ras homolog enriched in brain-like protein 1; Rheb-like protein 1; Rheb2
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