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The antibody against RIPK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against RIPK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-06321A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RIPK4 |
| Target Synonyms | DIK; PKK; PPS2; RIP4; ANKK2; NKRD3; ANKRD3; CHANDS; RIPK4 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 240-520 of human RIPK4 (NP_065690.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P57078 | Immunogen Sequence |
Uniprot Id
P57078
Target Species
Human
Target Name
RIPK4
Target Full Name
Receptor-interacting serine/threonine-protein kinase 4
Target Function
Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.
Target Involvement
Popliteal pterygium syndrome, lethal type (PPS-L)
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Target Protein Families
Protein kinase superfamily, TKL Ser/Thr protein kinase family
Target Tissue Specificity
Expressed in hair follicles and skin.
Target Synonyms
RIPK4; ANKRD3; DIK; Receptor-interacting serine/threonine-protein kinase 4; EC 2.7.11.1; Ankyrin repeat domain-containing protein 3; PKC-delta-interacting protein kinase
Target Background
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
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