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The antibody against RLBP1 was raised in rabbit using the Recombinant Human Retinaldehyde-binding protein 1 protein (10-91AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against RLBP1 was raised in rabbit using the Recombinant Human Retinaldehyde-binding protein 1 protein (10-91AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-09900A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RLBP1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Retinaldehyde-binding protein 1 protein (10-91AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P12271 |
Uniprot Id
P12271
Target Species
Human
Target Name
RLBP1
Target Full Name
Retinaldehyde-binding protein 1
Target Function
Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'.
Target Involvement
Bothnia retinal dystrophy (BRD); Rod-cone dystrophy Newfoundland (NFRCD); Retinitis punctata albescens (RPA)
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina.
Target Research Area
Others
Target Synonyms
Cellular retinaldehyde binding protein 1; Cellular retinaldehyde binding protein; Cellular retinaldehyde-binding protein; MGC3663; Retinaldehyde binding protein 1; Retinaldehyde-binding protein 1; RLBP 1; RLBP1; RLBP1_HUMAN
Target Background
The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens.
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