Rabbit anti-Human RMI1 Polyclonal Antibody

The antibody against RMI1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00439A

Number

Cat.No	ADA-00439A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RMI1
Target Synonyms	BLAP75; FAAP75; C9orf76; RMI1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Mouse liver	Application	ELISA, WB

Cat.No

ADA-00439A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RMI1

Target Synonyms

BLAP75; FAAP75; C9orf76; RMI1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Mouse liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2).	Target Species	Human
Uniprot ID	Q9H9A7	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human RMI1 (NP_079221.2).

Target Species

Human

Uniprot ID

Q9H9A7

Immunogen Sequence

Background Information

Uniprot Id

Q9H9A7
Target Species

Human
Target Name

RMI1
Target Full Name

RecQ-mediated genome instability protein 1
Target Function

Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
Target Subcellular Location

Nucleus. Note=Forms foci in response to DNA damage.
Target Protein Families

RMI1 family
Target Synonyms

BLAP75; BLM associated polypeptide 75 kDa; BLM associated protein 75 kDa; BLM-associated protein of 75 kDa; C9orf76; FAAP75; FLJ12888; Homolog of yeast RecQ mediated genome instability 1; RecQ mediated genome instability 1; RecQ-mediated genome instability protein 1; Rmi1; RMI1 homolog; RMI1 RecQ mediated genome instability 1 homolog; RMI1_HUMAN; RP11-346I8
Target Background

Predicted to enable nucleotide binding activity. Predicted to be involved in double-strand break repair via homologous recombination and resolution of meiotic recombination intermediates. Predicted to act upstream of or within glucose homeostasis; reduction of food intake in response to dietary excess; and response to glucose. Located in nuclear body.

Rabbit anti-Human RMI1 Polyclonal Antibody

Specifications

Immunogen Information

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