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The antibody against RMND5B was raised in rabbit using the Recombinant Human Protein RMD5 homolog B protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RMND5B was raised in rabbit using the Recombinant Human Protein RMD5 homolog B protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using RMND5B Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using RMND5B Antibody at dilution of 1:1002
| Cat.No | ADC-22494A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RMND5B |
| Target Synonyms | RMND5B antibody; UNQ2508/PRO5996 antibody; E3 ubiquitin-protein transferase RMND5B antibody; EC 2.3.2.27 antibody; Protein RMD5 homolog B antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein RMD5 homolog B protein (1-260AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96G75 |
Uniprot Id
Q96G75
Target Species
Human
Target Name
RMND5B
Target Full Name
E3 ubiquitin-protein transferase RMND5B
Target Function
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
Target Subcellular Location
Cytoplasm, cytosol.
Target Synonyms
RMND5B; UNQ2508/PRO5996; E3 ubiquitin-protein transferase RMND5B; EC 2.3.2.27; Protein RMD5 homolog B
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