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The antibody against RND3 was raised in rabbit using the Recombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against RND3 was raised in rabbit using the Recombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-14593A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RND3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Rho-related GTP-binding protein RhoE protein (152-239AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P61587 |
Uniprot Id
P61587
Target Species
Human
Target Name
RND3
Target Full Name
Rho-related GTP-binding protein RhoE
Target Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Target Subcellular Location
Golgi apparatus membrane; Peripheral membrane protein.
Target Protein Families
Small GTPase superfamily, Rho family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
ARHE; memB; Protein MemB; Ras homolog gene family member E; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rho-related GTP-binding protein RhoE; Rho8; RhoE; Rnd3; RND3_HUMAN; Small GTP binding protein Rho8
Target Background
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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