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Rabbit anti-Human ROBO4 Polyclonal Antibody

The antibody against ROBO4 was raised in rabbit using the Fusion protein of Human ROBO4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-29365A

The antibody against ROBO4 was raised in rabbit using the Fusion protein of Human ROBO4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-29365A ClonalityPolyclonal
Host SpeciesRabbitTarget NameROBO4
Target Synonymsaxon guidance receptor, homolog 4 (Drosophila) antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human ROBO4Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8WZ75
Background Information
  • Uniprot Id

    Q8WZ75

  • Target Species

    Human

  • Target Name

    ROBO4

  • Target Full Name

    Roundabout homolog 4

  • Target Function

    Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. Involved in the maintenance of endothelial barrier organization and function.

  • Target Protein Families

    Immunoglobulin superfamily, ROBO family

  • Target Tissue Specificity

    Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta.

  • Target Synonyms

    ECSM4; FLJ20798; Magic roundabout; MGC133352; MGC133353; MRB; Robo 4; ROBO4; ROBO4_HUMAN; Roundabout homolog 4; Roundabout homolog 4 magic roundabout; Roundabout homolog 4 Precursor; Roundabout, axon guidance receptor, homolog 4 (Drosophila)

  • Target Background

    Predicted to enable cell-cell adhesion mediator activity. Involved in angiogenesis and establishment of endothelial barrier. Located in extracellular exosome. Implicated in aortic valve disease 3.

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