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The antibody against RP2 was raised in rabbit using the Recombinant Human Protein XRP2 protein (1-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against RP2 was raised in rabbit using the Recombinant Human Protein XRP2 protein (1-350AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human kidney tissue using RP2 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using RP2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-17376A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RP2 |
| Target Synonyms | RP2 antibody; Protein XRP2 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein XRP2 protein (1-350AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75695 |
Uniprot Id
O75695
Target Species
Human
Target Name
RP2
Target Full Name
Protein XRP2
Target Function
Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.
Target Involvement
Retinitis pigmentosa 2 (RP2)
Target Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, cilium.
Target Protein Families
TBCC family
Target Tissue Specificity
Ubiquitous. Expressed in the rod and cone photoreceptors, extending from the tips of the outer segment (OS) through the inner segment (IS) and outer nuclear layer (ONL) and into the synaptic terminals of the outer plexiform layer (ONL). Also detected in t
Target Research Area
Neuroscience
Target Synonyms
RP2; Protein XRP2
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