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The antibody against RPA4 was raised in rabbit using the Recombinant Human Replication protein A 30 kDa subunit protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against RPA4 was raised in rabbit using the Recombinant Human Replication protein A 30 kDa subunit protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-50239A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RPA4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Replication protein A 30 kDa subunit protein (1-260AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13156 |
Uniprot Id
Q13156
Target Species
Human
Target Name
RPA4
Target Full Name
Replication protein A 30 kDa subunit
Target Function
As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Target Subcellular Location
Nucleus. Note=Localizes to DNA repair foci after DNA damage.
Target Protein Families
Replication factor A protein 2 family
Target Tissue Specificity
Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
HSU24186 ; MGC120333 ; MGC120334; p30; Replication factor A protein 4; Replication protein A 30 kDa subunit; RF A ; RF-A protein 4; RFA ; RFA4_HUMAN; RP A; RP-A p30; RPA; RPA4
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