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The antibody against RPGRIP1 was raised in rabbit using the Human RPGRIP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against RPGRIP1 was raised in rabbit using the Human RPGRIP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-52026A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RPGRIP1 |
| Target Synonyms | RPGRIP1 antibody; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 antibody; RPGR-interacting protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human RPGRIP1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96KN7 |
Uniprot Id
Q96KN7
Target Species
Human
Target Name
RPGRIP1
Target Full Name
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1
Target Function
May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
Target Involvement
Leber congenital amaurosis 6 (LCA6); Cone-rod dystrophy 13 (CORD13)
Target Subcellular Location
Cell projection, cilium.
Target Protein Families
RPGRIP1 family
Target Tissue Specificity
Strong expression in retina, with weaker expression in testis. Expressed in other neurons such as amacrine cells. Colocalizes with RGPR in the outer segment of rod photoreceptors and cone outer segments.
Target Synonyms
RPGRIP1; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; RPGR-interacting protein 1
Target Background
This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness.
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