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The antibody against RPL27 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human RPL27 (NP_000979.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against RPL27 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human RPL27 (NP_000979.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-09574A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RPL27 |
| Target Synonyms | L27; eL27; DBA16; RPL27 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-431, LO2, Mouse liver, Mouse thymus, U-87MG | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human RPL27 (NP_000979.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF | Uniprot ID | P61353 |
Uniprot Id
P61353
Target Species
Human
Target Name
RPL27
Target Full Name
Large ribosomal subunit protein eL27
Target Function
Component of the large ribosomal subunit. Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs.
Target Involvement
Diamond-Blackfan anemia 16 (DBA16)
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum.
Target Protein Families
Eukaryotic ribosomal protein eL27 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
RPL27; 60S ribosomal protein L27; Large ribosomal subunit protein eL27
Target Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
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