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The antibody against RPS6KC1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human p52 S6 kinase. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against RPS6KC1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human p52 S6 kinase. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
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Western blot analysis of HELA 293T lysis using p52 S6 kinase antibody.
| Cat.No | ADC-35629A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RPS6KC1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human p52 S6 kinase. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96S38 |
Uniprot Id
Q96S38
Target Species
Human
Target Name
RPS6KC1
Target Full Name
Ribosomal protein S6 kinase delta-1
Target Function
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Plays a role in the recruitment of PRDX3 to early endosomes.
Target Subcellular Location
Cytoplasm. Membrane. Early endosome.
Target Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family, S6 kinase subfamily
Target Tissue Specificity
Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.
Target Synonyms
52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1_HUMAN; Ribosomal protein S6 kinase 52kD polypeptide 1; Ribosomal protein S6 kinase 52kDa polypeptide 1; Ribosomal protein S6 kinase C1; Ribosomal protein S6 kinase delta 1; Ribosomal protein S6 kinase delta-1; Ribosomal S6 kinase like protein with two PSK domains 118 kDa protein; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK 118; RPK118; RPS6KC1; RSKL1; S6K-delta-1; S6PKh1; SPHK1 binding protein; SPHK1-binding protein
Target Background
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria.
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