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Rabbit anti-Human RRN3 Polyclonal Antibody

The antibody against RRN3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 550-651 of human RRN3 (NP_060897.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01570A

The antibody against RRN3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 550-651 of human RRN3 (NP_060897.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01570A ClonalityPolyclonal
Host SpeciesRabbitTarget NameRRN3
Target SynonymsTIFIA; A-270G1.2; RRN3FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Mouse brain, Mouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 550-651 of human RRN3 (NP_060897.3).Target SpeciesHuman
Immunogen SequenceQICTNPLDTFFPFDPCVLKRSKKFIDPIYQVWEDMSAEELQEFKKPMKKDIVEDEDDDFLKGEVPQNDTVIGITPSSFDTHFRSPSSSVGSPPVLYMQPSPLUniprot IDQ9NYV6
Background Information
  • Uniprot Id

    Q9NYV6

  • Target Species

    Human

  • Target Name

    RRN3

  • Target Full Name

    RNA polymerase I-specific transcription initiation factor RRN3

  • Target Function

    Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.

  • Target Subcellular Location

    Nucleus, nucleolus.

  • Target Protein Families

    RRN3 family

  • Target Synonyms

    AL023001; DKFZp566E104; E130302O19Rik; MGC104238; R75565; RGD1305001; RNA polymerase I-specific transcription initiation factor RRN3; Rrn3; RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae); RRN3_HUMAN; TIF-IA; TIF1A; TIFIA; Transcription Initiation Factor 1A; Transcription initiation factor IA; Transcription initiation factor TIF IA

  • Target Background

    Enables RNA polymerase I core promoter sequence-specific DNA binding activity. Predicted to be involved in transcription initiation from RNA polymerase I promoter. Predicted to act upstream of or within several processes, including DNA-templated transcription, initiation; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of transcription, DNA-templated. Located in nucleolus.

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