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The antibody against RTCA was raised in rabbit using the Recombinant Human RNA 3'-terminal phosphate cyclase protein (167-379AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against RTCA was raised in rabbit using the Recombinant Human RNA 3′-terminal phosphate cyclase protein (167-379AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-23733A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RTCA |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | HRP conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human RNA 3'-terminal phosphate cyclase protein (167-379AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00442 |
Uniprot Id
O00442
Target Species
Human
Target Name
RTCA
Target Full Name
RNA 3'-terminal phosphate cyclase
Target Function
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
Target Subcellular Location
Nucleus, nucleoplasm.
Target Protein Families
RNA 3'-terminal cyclase family, Type 1 subfamily
Target Tissue Specificity
Ubiquitous.
Target Synonyms
RTCA; RPC; RPC1; RTC1; RTCD1; RNA 3'-terminal phosphate cyclase; RNA cyclase; RNA-3'-phosphate cyclase; EC 6.5.1.4; RNA terminal phosphate cyclase domain-containing protein 1; RTC domain-containing protein 1
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