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The antibody against RUSC1 was raised in rabbit using the Recombinant Human RUN and SH3 domain-containing protein 1 protein (231-433AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against RUSC1 was raised in rabbit using the Recombinant Human RUN and SH3 domain-containing protein 1 protein (231-433AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human colon cancer using RUSC1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using RUSC1 Antibody at dilution of 1:1002
Immunofluorescent analysis of MCF-7 cells using RUSC1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-23722A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RUSC1 |
| Target Synonyms | RUSC1 antibody; NESCARUN and SH3 domain-containing protein 1 antibody; New molecule containing SH3 at the carboxy-terminus antibody; Nesca antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human RUN and SH3 domain-containing protein 1 protein (231-433AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BVN2 |
Uniprot Id
Q9BVN2
Target Species
Human
Target Name
RUSC1
Target Full Name
AP-4 complex accessory subunit RUSC1
Target Function
Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network. Signaling adapter which plays a role in neuronal differentiation. Involved in regulation of NGF-dependent neurite outgrowth. May play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway.
Target Subcellular Location
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Early endosome. Cell junction, synapse, postsynaptic density. Golgi apparatus.
Target Tissue Specificity
Predominantly expressed in brain.
Target Synonyms
RUSC1; NESCARUN and SH3 domain-containing protein 1; New molecule containing SH3 at the carboxy-terminus; Nesca
Target Background
Predicted to enable actin binding activity. Involved in protein polyubiquitination. Located in cytosol.
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