Rabbit anti-Human RXFP2 Polyclonal Antibody

The antibody against RXFP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05736A

Number

Cat.No	ADA-05736A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	RXFP2
Target Synonyms	LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2; RXFP2	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, Rat kidney	Application	ELISA, WB

Cat.No

ADA-05736A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

RXFP2

Target Synonyms

LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2; RXFP2

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, Rat kidney

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1).	Target Species	Human
Immunogen Sequence	CGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKA	Uniprot ID	Q8WXD0

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1).

Target Species

Human

Immunogen Sequence

CGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKA

Uniprot ID

Q8WXD0

Background Information

Uniprot Id

Q8WXD0
Target Species

Human
Target Name

RXFP2
Target Full Name

Relaxin receptor 2
Target Function

Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
Target Involvement

Cryptorchidism (CRYPTO)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 1 family
Target Tissue Specificity

Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.
Target Research Area

Others
Target Synonyms

RXFP2; GPR106; GREAT; LGR8; Relaxin receptor 2; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2
Target Background

This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human RXFP2 Polyclonal Antibody

Specifications

Immunogen Information

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