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The antibody against RXFP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RXFP3 (NP_057652.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against RXFP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RXFP3 (NP_057652.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01404A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RXFP3 |
| Target Synonyms | SALPR; RLN3R1; RXFPR3; GPCR135; RXFP3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, BxPC-3, MCF7, Mouse brain, Rat pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RXFP3 (NP_057652.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGSGGAESADTEARV | Uniprot ID | Q9NSD7 |
Uniprot Id
Q9NSD7
Target Species
Human
Target Name
RXFP3
Target Full Name
Relaxin-3 receptor 1
Target Function
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high leve
Target Synonyms
RXFP3; GPCR135; RLN3R1; SALPR; Relaxin-3 receptor 1; RLN3 receptor 1; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; Relaxin family peptide receptor 3; Somatostatin- and angiotensin-like peptide receptor
Target Background
Predicted to enable G protein-coupled peptide receptor activity. Involved in positive regulation of cytokinesis. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane.
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