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The antibody against RYK was raised in rabbit using the Recombinant Human Tyrosine-protein kinase RYK protein (494-586AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against RYK was raised in rabbit using the Recombinant Human Tyrosine-protein kinase RYK protein (494-586AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-05067A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | RYK |
| Target Synonyms | RYK; JTK5A; Tyrosine-protein kinase RYK | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Tyrosine-protein kinase RYK protein (494-586AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P34925 |
Uniprot Id
P34925
Target Species
Human
Target Name
RYK
Target Full Name
Tyrosine-protein kinase RYK
Target Function
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm.
Target Protein Families
Protein kinase superfamily, Tyr protein kinase family
Target Tissue Specificity
Observed in all the tissues examined.
Target Synonyms
RYK; JTK5A; Tyrosine-protein kinase RYK
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