Rabbit anti-Human S100A2 Polyclonal Antibody

Uniprot Id

P29034

Target Species

Human

Target Name

S100A2

Target Full Name

Protein S100-A2

Target Function

May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.

Target Protein Families

S-100 family

Target Tissue Specificity

A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.

Target Synonyms

CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium binding protein A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN

Target Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.