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Rabbit anti-Human S1PR3 Polyclonal Antibody

The antibody against S1PR3 was raised in rabbit using the Synthetic peptide of Human S1PR3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-27370A

The antibody against S1PR3 was raised in rabbit using the Synthetic peptide of Human S1PR3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-27370A ClonalityPolyclonal
Host SpeciesRabbitTarget NameS1PR3
Target SynonymsS1PR3; EDG3; Sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human S1PR3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ99500
Background Information
  • Uniprot Id

    Q99500

  • Target Species

    Human

  • Target Name

    S1PR3

  • Target Full Name

    Sphingosine 1-phosphate receptor 3

  • Target Function

    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.

  • Target Synonyms

    S1PR3; EDG3; Sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3

  • Target Background

    This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.

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