Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against SAA1 was raised in rabbit using the Recombinant Human Serum amyloid A-1 protein (20-122AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against SAA1 was raised in rabbit using the Recombinant Human Serum amyloid A-1 protein (20-122AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry analysis of human liver tissue using SAA1 Antibody at dilution of 1:100
Immunohistochemistry analysis of human small intestine tissue using SAA1 Antibody at dilution of 1:1002
| Cat.No | ADC-51010A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SAA1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serum amyloid A-1 protein (20-122AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P0DJI8 |
Uniprot Id
P0DJI8
Target Species
Human
Target Name
SAA1
Target Full Name
Serum amyloid A-1 protein
Target Function
Major acute phase protein.
Target Involvement
Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
Target Subcellular Location
Secreted.
Target Protein Families
SAA family
Target Tissue Specificity
Expressed by the liver; secreted in plasma (at protein level).
Target Synonyms
SAA; PIG4; SAA2; TP53I4; SAA1
Target Background
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
