Rabbit anti-Human SARA Monoclonal Antibody

The antibody against SARA was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human SARA (O95405) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-13354A

Number

Cat.No	ADA-13354A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	SARA
Target Synonyms	NSP; SARA; MADHIP; SMADIP; PPP1R173	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse testis, Rat lung, Rat testis, SH-SY5Y	Application	ELISA, WB, IHC-P

Cat.No

ADA-13354A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

SARA

Target Synonyms

NSP; SARA; MADHIP; SMADIP; PPP1R173

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse testis, Rat lung, Rat testis, SH-SY5Y

Application

ELISA, WB, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SARA (O95405).	Target Species	Human
Immunogen Sequence	MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESAVSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEI	Uniprot ID	O95405

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SARA (O95405).

Target Species

Human

Immunogen Sequence

MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESAVSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEI

Uniprot ID

O95405

Background Information

Uniprot Id

O95405
Target Species

Human
Target Name

ZFYVE9
Target Full Name

Zinc finger FYVE domain-containing protein 9
Target Function

Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
Target Subcellular Location

Cytoplasm. Early endosome membrane.
Target Tissue Specificity

Ubiquitous. In the brain found primarily in the cerebrovascular smooth muscle cells and reactive astrocytes.
Target Synonyms

CG15667; hSARA; LD33044p; Madh-interacting protein; MADHIP; Mothers against decapentaplegic homolog-interacting protein; Novel serine protease; NSP; Receptor activation anchor; SAR1; SARA; SARA1; Smad anchor for receptor activation; SMADIP; ZFYV9_HUMAN; ZFYVE9; Zinc finger FYVE domain-containing protein 9
Target Background

This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human SARA Monoclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human SARA Monoclonal Antibody Now

Related Products