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The antibody against SCG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-320 of human SCG2 (NP_003460.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SCG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-320 of human SCG2 (NP_003460.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-09485A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCG2 |
| Target Synonyms | SN; CHGC; EM66; SgII; SCG2 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, SW620 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 30-320 of human SCG2 (NP_003460.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P13521 | Immunogen Sequence |
Uniprot Id
P13521
Target Species
Human
Target Name
SCG2
Target Full Name
Secretogranin-2
Target Function
Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
Target Subcellular Location
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Target Protein Families
Chromogranin/secretogranin protein family
Target Research Area
Neuroscience
Target Synonyms
CHGC; Chromogranin C; Chromogranin-C; EM66; SCG2; SCG2_HUMAN; Secretogranin II; Secretogranin-2; Secretoneurin; SGII; SN
Target Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
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