Rabbit anti-Human SCG3 Polyclonal Antibody

The antibody against SCG3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10976A

Number

Cat.No	ADA-10976A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SCG3
Target Synonyms	SGIII; SCG3	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse heart, Rat brain, Rat heart, 22Rv1, HepG2, Mouse brain, Mouse lung, Rat lung	Application	ELISA, WB

Cat.No

ADA-10976A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SCG3

Target Synonyms

SGIII; SCG3

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse heart, Rat brain, Rat heart, 22Rv1, HepG2, Mouse brain, Mouse lung, Rat lung

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2).	Target Species	Human
Uniprot ID	Q8WXD2	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 199-468 of human SCG3 (NP_037375.2).

Target Species

Human

Uniprot ID

Q8WXD2

Immunogen Sequence

Background Information

Uniprot Id

Q8WXD2
Target Species

Human
Target Name

SCG3
Target Full Name

Secretogranin-3
Target Function

Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Target Subcellular Location

Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted.
Target Tissue Specificity

Expressed in brain, heart, kidney, liver and skeletal muscle.
Target Synonyms

1B1075; AI385542; Chgd; SCG3; SCG3_HUMAN; Secretogranin III; Secretogranin-3; SGCG; SgIII
Target Background

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human SCG3 Polyclonal Antibody

Specifications

Immunogen Information

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