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The antibody against SCG3 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human Sg III. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against SCG3 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human Sg III. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of mouse heart mouse kidney cells using Sg III Polyclonal Antibody
| Cat.No | ADC-37207A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCG3 |
| Target Synonyms | 1B1075 antibody; AI385542 antibody; Chgd antibody; SCG3 antibody; SCG3_HUMAN antibody; Secretogranin III antibody; Secretogranin-3 antibody; SGCG antibody; SgIII antibody | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human Sg III. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WXD2 |
Uniprot Id
Q8WXD2
Target Species
Human
Target Name
SCG3
Target Full Name
Secretogranin-3
Target Function
Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted.
Target Tissue Specificity
Expressed in brain, heart, kidney, liver and skeletal muscle.
Target Synonyms
1B1075; AI385542; Chgd; SCG3; SCG3_HUMAN; Secretogranin III; Secretogranin-3; SGCG; SgIII
Target Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene.
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