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The antibody against SCN2B was raised in rabbit using the Human SCN2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against SCN2B was raised in rabbit using the Human SCN2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-47251A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SCN2B |
| Target Synonyms | SCN2B; UNQ326/PRO386; Sodium channel subunit beta-2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human SCN2B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60939 |
Uniprot Id
O60939
Target Species
Human
Target Name
SCN2B
Target Full Name
Sodium channel regulatory subunit beta-2
Target Function
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
Target Involvement
Atrial fibrillation, familial, 14 (ATFB14)
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Sodium channel auxiliary subunit SCN2B (TC 8.A.17) family
Target Tissue Specificity
Brain specific.
Target Synonyms
SCN2B; UNQ326/PRO386; Sodium channel subunit beta-2
Target Background
The protein encoded by this gene is the beta 2 subunit of the type II voltage-gated sodium channel. The encoded protein is involved in cell-cell adhesion and cell migration. Defects in this gene can be a cause of Brugada Syndrome, atrial fibrillation, or sudden infant death syndrome.
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