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The antibody against SDCCAG8 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human NY-CO-8. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against SDCCAG8 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human NY-CO-8. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-36559A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SDCCAG8 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human NY-CO-8. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86SQ7 |
Uniprot Id
Q86SQ7
Target Species
Human
Target Name
SDCCAG8
Target Full Name
Serologically defined colon cancer antigen 8
Target Function
Plays a role in the establishment of cell polarity and epithelial lumen formation. Plays also an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
Target Involvement
Senior-Loken syndrome 7 (SLSN7); Bardet-Biedl syndrome 16 (BBS16)
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell junction. Note=Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.; [Isoform 2]: Cytoplasm.
Target Tissue Specificity
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
Target Synonyms
Antigen NY CO 8; Antigen NY-CO-8; BBS16; CCCAP; CCCAP SLSN7; Centrosomal colon cancer autoantigen protein; hCCCAP; HSPC085; NPHP10; NPHP10 gene; NY-CO-8; Sdccag8; SDCG8_HUMAN; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7; SLSN7 gene
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