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The antibody against SEMA3B was raised in rabbit using the Recombinant Human Semaphorin-3B protein (570-749AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against SEMA3B was raised in rabbit using the Recombinant Human Semaphorin-3B protein (570-749AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human skin tissue using SEMA3B Antibody at dilution of 1:100
| Cat.No | ADC-17335A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SEMA3B |
| Target Synonyms | SEM3B_HUMAN antibody; Sema A(V) antibody; Sema V antibody; Sema3b antibody; Semaphorin V antibody; Semaphorin-3B antibody; Semaphorin-V antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Semaphorin-3B protein (570-749AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13214 |
Uniprot Id
Q13214
Target Species
Human
Target Name
SEMA3B
Target Full Name
Semaphorin-3B
Target Function
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Target Subcellular Location
Secreted. Endoplasmic reticulum. Note=Accumulates in the endoplasmic reticulum.
Target Protein Families
Semaphorin family
Target Tissue Specificity
Expressed abundantly but differentially in a variety of neural and nonneural tissues.
Target Research Area
Cancer
Target Synonyms
SEM3B_HUMAN; Sema A(V); Sema V; Sema3b; Semaphorin V; Semaphorin-3B; Semaphorin-V
Target Background
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants.
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