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Rabbit anti-Human SEPT12 Polyclonal Antibody

The antibody against SEPT12 was raised in rabbit using the Recombinant Human Septin-12 protein (1-358AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

ADC-19310A

The antibody against SEPT12 was raised in rabbit using the Recombinant Human Septin-12 protein (1-358AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.

$299.00

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Specifications


Cat.No ADC-19310A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSEPT12
Target SynonymsSEP12_HUMAN antibody; SEPT12 antibody; Septin-12 antibody; Septin12 antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Septin-12 protein (1-358AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8IYM1
Background Information
  • Uniprot Id

    Q8IYM1

  • Target Species

    Human

  • Target Name

    SEPT12

  • Target Full Name

    Septin-12

  • Target Function

    Filament-forming cytoskeletal GTPase. Involved in spermatogenesis. Involved in the morphogenesis of sperm heads and the elongation of sperm tails probably implicating the association with alpha- and beta-tubulins. Forms a filamentous structure with SEPTIN7, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. May play a role in cytokinesis (Potential).

  • Target Involvement

    Spermatogenic failure 10 (SPGF10)

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Nucleus. Cell projection, cilium, flagellum.

  • Target Protein Families

    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family

  • Target Tissue Specificity

    Widely expressed. Expressed in lymph node.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    SEP12_HUMAN; SEPT12; Septin-12; Septin12

  • Target Background

    This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene.

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