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The antibody against SERPINA10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against SERPINA10 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-00445A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERPINA10 |
| Target Synonyms | PZI; ZPI; SERPINA10 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 165-444 of human SERPINA10 (NP_001094077.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UK55 | Immunogen Sequence |
Uniprot Id
Q9UK55
Target Species
Human
Target Name
SERPINA10
Target Full Name
Protein Z-dependent protease inhibitor
Target Function
Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors.
Target Subcellular Location
Secreted.
Target Protein Families
Serpin family
Target Tissue Specificity
Expressed by the liver and secreted in plasma.
Target Synonyms
Protein Z dependent protease inhibitor; Protein Z dependent protease inhibitor precursor; Protein Z-dependent protease inhibitor; PZ dependent protease inhibitor; PZ-dependent protease inhibitor; PZI; serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 10; Serpin A10; Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 10; SERPINA 10; SERPINA10; ZPI; ZPI_HUMAN
Target Background
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.
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