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The antibody against SERPINA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SERPINA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03095A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERPINA7 |
| Target Synonyms | TBG; TBGQTL; SERPINA7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse pancreas, Muose heart, Rat kidney, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P05543 | Immunogen Sequence |
Uniprot Id
P05543
Target Species
Human
Target Name
SERPINA7
Target Full Name
Thyroxine-binding globulin
Target Function
Major thyroid hormone transport protein in serum.
Target Subcellular Location
Secreted.
Target Protein Families
Serpin family
Target Tissue Specificity
Expressed by the liver and secreted in plasma.
Target Synonyms
TBG; TBGQTL; SERPINA7
Target Background
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3, 5, 3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
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