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Rabbit anti-Human SERPINA7 Polyclonal Antibody

The antibody against SERPINA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03095A

The antibody against SERPINA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03095A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSERPINA7
Target SynonymsTBG; TBGQTL; SERPINA7FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse pancreas, Muose heart, Rat kidney, Rat liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 146-415 of human SERPINA7 (NP_000345.2).Target SpeciesHuman
Uniprot IDP05543Immunogen Sequence
Background Information
  • Uniprot Id

    P05543

  • Target Species

    Human

  • Target Name

    SERPINA7

  • Target Full Name

    Thyroxine-binding globulin

  • Target Function

    Major thyroid hormone transport protein in serum.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Serpin family

  • Target Tissue Specificity

    Expressed by the liver and secreted in plasma.

  • Target Synonyms

    TBG; TBGQTL; SERPINA7

  • Target Background

    There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3, 5, 3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

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