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The antibody against SERPINB3 was raised in rabbit using the Recombinant Human Serpin B3 protein (2-383AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against SERPINB3 was raised in rabbit using the Recombinant Human Serpin B3 protein (2-383AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-44649A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERPINB3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serpin B3 protein (2-383AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P29508 |
Uniprot Id
P29508
Target Species
Human
Target Name
SERPINB3
Target Full Name
Serpin B3
Target Function
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Target Subcellular Location
Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.
Target Protein Families
Serpin family, Ov-serpin subfamily
Target Tissue Specificity
Squamous cells. Expressed in some hepatocellular carcinoma (at protein level).
Target Synonyms
SCC; T4-A; SCCA1; SSCA1; SCCA-1; HsT1196; SCCA-PD; SSCA1/SerpinB3
Target Background
Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus.
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