Rabbit anti-Human SERPINB5 Polyclonal Antibody

The antibody against SERPINB5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 21-189 of human SERPINB5 (NP_002630.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13642A

Number

Cat.No	ADA-13642A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SERPINB5
Target Synonyms	PI5; maspin; B5	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa	Application	ELISA, WB

Cat.No

ADA-13642A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SERPINB5

Target Synonyms

PI5; maspin; B5

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 21-189 of human SERPINB5 (NP_002630.2).	Target Species	Human
Immunogen Sequence	EKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNK	Uniprot ID	P36952

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 21-189 of human SERPINB5 (NP_002630.2).

Target Species

Human

Immunogen Sequence

EKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNK

Uniprot ID

P36952

Background Information

Uniprot Id

P36952
Target Species

Human
Target Name

SERPINB5
Target Full Name

Serpin B5
Target Function

Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Target Subcellular Location

Secreted, extracellular space.
Target Protein Families

Serpin family, Ov-serpin subfamily
Target Tissue Specificity

Normal mammary epithelial cells.
Target Synonyms

Maspin; Ovalbumin; Peptidase inhibitor 5; PI-5; PI5; protease inhibitor 5 (maspin); Protease inhibitor 5; Serine (or cysteine) peptidase inhibitor; clade B; member 5; serine (or cysteine) proteinase inhibitor; clade B (ovalbumin); member 5; Serpin B5; serpin family B member 5; Serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; Serpinb5; SPB5_HUMAN; Spi5; Spi7
Target Background

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to act upstream of or within several processes, including extracellular matrix organization; prostate gland morphogenesis; and regulation of epithelial cell proliferation. Located in cytoplasm. Biomarker of hepatocellular carcinoma.

Rabbit anti-Human SERPINB5 Polyclonal Antibody

Specifications

Immunogen Information

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