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The antibody against SERTAD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SERTAD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01147A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SERTAD1 |
| Target Synonyms | SEI1; TRIPBR1; TRIP-Br1; SERTAD1 | Form | Liquid |
| Species Reactivity | Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat lung, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human SERTAD1 (NP_037508.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UHV2 | Immunogen Sequence |
Uniprot Id
Q9UHV2
Target Species
Human
Target Name
SERTAD1
Target Full Name
SERTA domain-containing protein 1
Target Function
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Target Synonyms
CDK4 binding protein p34SEI; CDK4 binding protein p34SEI1; CDK4-binding protein p34SEI1; SEI-1; SEI1; SERTA domain containing 1; SERTA domain-containing protein 1; SERTAD1; SRTD1_HUMAN; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP Br1; TRIP-Br1
Target Background
Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus.
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