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The antibody against SETD3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 72-329 of human SETD3 (NP_115609.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.
The antibody against SETD3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 72-329 of human SETD3 (NP_115609.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.
| Cat.No | ADA-07820A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SETD3 |
| Target Synonyms | hSETD3; C14orf154; SETD3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat | Application | ELISA, WB, IP |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 72-329 of human SETD3 (NP_115609.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q86TU7 | Immunogen Sequence |
Uniprot Id
Q86TU7
Target Species
Human
Target Name
SETD3
Target Full Name
Actin-histidine N-methyltransferase
Target Function
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SETD3 subfamily
Target Synonyms
C14orf154; Chromosome 14 open reading frame 154 ; DKFZp761E1415; FLJ23027; Histone lysine N methyltransferase setd3; Histone-lysine N-methyltransferase setd3; MGC87236; SET domain containing 3; SET domain containing protein 3; SET domain-containing protein 3; SETD 3; Setd3; SETD3_HUMAN
Target Background
Enables protein-L-histidine N-tele-methyltransferase activity. Involved in actin modification and peptidyl-histidine methylation. Located in cytoplasm.
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