Rabbit anti-Human SF3A3 Monoclonal Antibody

The antibody against SF3A3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3A3 (Q12874) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13400A

Number

Cat.No	ADA-13400A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	SF3A3
Target Synonyms	PRP9; PRPF9; SAP61; SF3a60; SF3A3	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, NIH/3T3, A-431, K-562, Mouse brain, Mouse liver, Raji	Application	ELISA, WB

Cat.No

ADA-13400A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

SF3A3

Target Synonyms

PRP9; PRPF9; SAP61; SF3a60; SF3A3

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, NIH/3T3, A-431, K-562, Mouse brain, Mouse liver, Raji

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3A3 (Q12874).	Target Species	Human
Immunogen Sequence	METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPN	Uniprot ID	Q12874

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3A3 (Q12874).

Target Species

Human

Immunogen Sequence

METILEQQRRYHEEKERLMDVMAKEMLTKKSTLRDQINSDHRTRAMQDRYMEVSGNLRDLYDDKDGLRKEELNAISGPNEFAEFYNRLKQIKEFHRKHPN

Uniprot ID

Q12874

Background Information

Uniprot Id

Q12874
Target Species

Human
Target Name

SF3A3
Target Full Name

Splicing factor 3A subunit 3
Target Function

Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.
Target Subcellular Location

Nucleus speckle. Nucleus.
Target Protein Families

SF3A3 family
Target Tissue Specificity

Ubiquitous.
Target Synonyms

SF3A3; SAP61; Splicing factor 3A subunit 3; SF3a60; Spliceosome-associated protein 61; SAP 61
Target Background

This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human SF3A3 Monoclonal Antibody

Specifications

Immunogen Information

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